Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985934 | 0.86 | MAPT (0.43) | MAPTSLC2A1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL6991899 | 0.86 | MAPT (0.51) | MAPTSLC2A1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL6991932 | 0.86 | MAPT (0.41) | MAPTSLC2A1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL5210605 | 0.85 | CFTR (0.55) | MAPTL3MBTL1ALDH1A1OPRK1KMT2A | |
| SCHEMBL6238400 | 0.85 | SLC2A1 (0.46) | MAPTSLC2A1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL6990533 | 0.85 | SLC2A1 (0.53) | MAPTSLC2A1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5214358 | 0.81 | PPARG (0.55) | MAPTL3MBTL1ALDH1A1TP53LMNA | |
| SCHEMBL5215161 | 0.81 | USP2 (0.53) | MAPTSLC2A1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL6985928 | 0.79 | KDM5B (0.49) | MAPTL3MBTL1ALDH1A1ALKBH2ALKBH5 | |
| SCHEMBL5808527 | 0.79 | ALDH1A1 (0.69) | MAPTL3MBTL1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |