Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998457 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL20669916 | 0.79 | DAO (0.59) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8189335 | 0.76 | LMNA (0.51) | LMNACYP1A2GAAHPGDSIRT1 | |
| SCHEMBL2372152 | 0.76 | LMNA (0.51) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL31384349 | 0.75 | CSF1R (0.70) | MEN1KMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL10673573 | 0.74 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL28787087 | 0.73 | LMNA (0.56) | MEN1KMT2ALMNACYP1A2GAA | |
| SCHEMBL27785105 | 0.73 | LMNA (0.56) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL25430492 | 0.73 | SIRT1 (0.52) | LMNACYP1A2GAAHPGDSIRT1 | |
| SCHEMBL7114815 | 0.73 | ALDH1A1 (0.67) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6114349-A | Substituted quinoline derivatives with antiviral action | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |