Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991969 | 0.81 | DYRK1A (0.44) | KDM4ERXFP1CDK1CCNB1LMNA | |
| SCHEMBL6998457 | 0.74 | ALDH1A1 (0.50) | KDM4EHSD17B10LMNAHPGDALDH1A1 | |
| SCHEMBL1092493 | 0.74 | ALDH1A1 (0.52) | KDM4ELMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL3641835 | 0.73 | DAO (0.49) | KDM4ERXFP1L3MBTL1MEN1KMT2A | |
| SCHEMBL6994828 | 0.72 | LMNA (0.37) | KDM4EHSD17B10LMNAHPGDSMN1; SMN2 | |
| SCHEMBL11734356 | 0.69 | KDM4E (0.43) | KDM4EHSD17B10RXFP1CDK1CCNB1 | |
| SCHEMBL4090248 | 0.68 | CDK1 (0.57) | KDM4ERXFP1CDK1CCNB1LMNA | |
| SCHEMBL13034152 | 0.67 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL26741264 | 0.67 | ALDH1A1 (0.44) | KDM4ELMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL4647196 | 0.67 | ALDH1A1 (0.61) | KDM4EHSD17B10LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| EP-1003724-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | Aventis Pharma Deutschland GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1997037977-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-16 | — | — | WO | disclosed |