Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994625 | 0.89 | POLB (0.53) | POLBMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL6999604 | 0.84 | MAOB (0.57) | TAS1R3TAS1R1POLBMAOBCACNA1G | |
| SCHEMBL6996652 | 0.74 | ROCK2 (0.42) | NAMPTRAB9AKMT2AALDH1A1ROCK2 | |
| SCHEMBL6990480 | 0.74 | ROCK2 (0.42) | NAMPTRAB9AKMT2AALDH1A1ROCK2 | |
| SCHEMBL7000901 | 0.72 | MAOB (0.72) | POLBMAOBNAMPTMEN1KMT2A | |
| SCHEMBL6642670 | 0.72 | TAS1R3 (0.45) | TAS1R3TAS1R1POLBNAMPTMEN1 | |
| SCHEMBL26049725 | 0.72 | LTA4H (0.43) | ROCK2ROCK1 | |
| SCHEMBL7020699 | 0.69 | TAS1R3 (0.52) | TAS1R3TAS1R1POLBCACNA1GCACNA1H | |
| SCHEMBL947356 | 0.68 | TAS1R3 (0.56) | TAS1R3TAS1R1POLBCACNA1GCACNA1H | |
| SCHEMBL7015349 | 0.66 | MEN1 (0.55) | TAS1R3TAS1R1POLBCACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037633-B1 | ANTIVIRAL COMPOUNDS | IAF BIOCHEM INT (CA) | 2003-09-10 | — | — | EP | claimed |