Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357715 | 0.82 | HSD17B1 (0.34) | ALDH1A1HSD17B10MAPTPGRRAB9A | |
| SCHEMBL7615770 | 0.72 | ALDH1A1 (0.37) | NPC1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL29764 | 0.71 | NPC1 (0.52) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12982405 | 0.69 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12170048 | 0.69 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12982161 | 0.69 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL120939 | 0.69 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL11997754 | 0.69 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL7615765 | 0.68 | CYP2A6 (0.41) | ALDH1A1HSD17B10MAPTCHRM2CHRM4 | |
| SCHEMBL5889850 | 0.68 | NPC1 (0.35) | NPC1ALDH1A1HSD17B10MAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337520-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | Ciba SC Holding AG (CH) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002042281-A1 | SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-05-30 | — | — | WO | disclosed |
| US-5010090-A | N-(butenyl substituted) azaheterocyclic carboxylic acids | NOVO NORDISK A/S. (DK) | 1991-04-23 | — | — | US | disclosed |