Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10607599 | 0.87 | MAPT (0.54) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL10654204 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL1265785 | 0.79 | ALKBH5 (0.55) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL395368 | 0.77 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL393039 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL10698670 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL10608289 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL144358 | 0.75 | LCK (0.95) | ALDH1A1MAPTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL10834947 | 0.75 | LCK (0.95) | ALDH1A1MAPTKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL940282 | 0.75 | LCK (0.95) | ALDH1A1MAPTKDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | claimed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | claimed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| US-7985266-B2 | Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2011-07-26 | — | — | US | disclosed |
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | NOXELL CORPORATION | 2011-02-17 | — | — | US | disclosed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110035886-A1 | Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof | KRT18, LPO, KRTCAP2 | ALDH1A1 354/4885MAPT 547/4885KDM4E 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.