Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992741 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPK1ATMFOLH1KMT2A | |
| SCHEMBL6990895 | 0.90 | TAS1R3 (0.55) | FOLH1TAS1R3TAS1R1 | |
| SCHEMBL7959631 | 0.90 | TAS1R3 (0.55) | FOLH1TAS1R3TAS1R1 | |
| SCHEMBL8744827 | 0.88 | MAPK1 (0.56) | ALDH1A1MAPK1FOLH1KMT2APOLB | |
| SCHEMBL8744819 | 0.88 | MAPK1 (0.56) | ALDH1A1MAPK1FOLH1KMT2APOLB | |
| SCHEMBL6990345 | 0.86 | SHMT2 (0.44) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL6990342 | 0.86 | SHMT2 (0.44) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL6995119 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPK1ATMFOLH1KMT2A | |
| SCHEMBL6995117 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPK1ATMFOLH1KMT2A | |
| SCHEMBL7094314 | 0.84 | MAPK1 (0.44) | ALDH1A1MAPK1KMT2APYGLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |