Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985928 | 0.92 | KDM5B (0.49) | MAPTALDH1A1L3MBTL1NR3C2ALKBH5 | |
| SCHEMBL6239726 | 0.89 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1ALKBH5FTO | |
| SCHEMBL6235518 | 0.86 | ALDH1A1 (0.49) | MAPTALDH1A1L3MBTL1SLC2A1ALKBH5 | |
| SCHEMBL6989792 | 0.86 | MEN1 (0.45) | MAPTALDH1A1L3MBTL1ALKBH5FTO | |
| SCHEMBL6992829 | 0.86 | MAPT (0.46) | MAPTALDH1A1L3MBTL1SLC2A1ALKBH5 | |
| SCHEMBL6990114 | 0.86 | LPAR1 (0.49) | ALDH1A1NR3C2SLC2A1SMN1; SMN2HTT | |
| SCHEMBL6239722 | 0.82 | KDM5B (0.49) | MAPTALDH1A1L3MBTL1ALKBH5FTO | |
| SCHEMBL6993032 | 0.81 | KMT2A (0.49) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16569986 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1L3MBTL1ALKBH5FTO | |
| SCHEMBL6235516 | 0.79 | KDM4C (0.49) | MAPTALDH1A1L3MBTL1ALKBH5FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |