Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993952 | 0.95 | HSD11B1 (0.59) | BRD4HSD11B1 | |
| SCHEMBL6990217 | 0.80 | PTGS2 (0.47) | BRD4HSD11B1 | |
| SCHEMBL6987934 | 0.77 | PTGS1 (0.52) | BRD4 | |
| SCHEMBL6998152 | 0.76 | KDM4E (0.44) | BRD4HSD11B1KDM4EPLA2G10ALDH1A1 | |
| SCHEMBL6996631 | 0.76 | KDM4E (0.44) | BRD4HSD11B1KDM4EPLA2G10ALDH1A1 | |
| SCHEMBL12723082 | 0.74 | PARP1 (0.52) | BRD4HSD11B1MAPK10HSD17B10 | |
| SCHEMBL12723081 | 0.74 | BRD4 (0.50) | BRD4HSD11B1LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8015300 | 0.74 | KDM4E (0.43) | BRD4HSD11B1KDM4EPLA2G10ALDH1A1 | |
| SCHEMBL12723097 | 0.73 | PARP1 (0.48) | BRD4HSD11B1LMNAKDM4EALDH1A1 | |
| SCHEMBL7685336 | 0.73 | BRD4 (0.68) | BRD4HSD11B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921119-B1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0921119-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-09 | — | — | EP | disclosed |