Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992970 | 0.95 | BRD4 (0.56) | HSD11B1BRD4 | |
| SCHEMBL6990217 | 0.84 | PTGS2 (0.47) | HSD11B1BRD4 | |
| SCHEMBL6990226 | 0.78 | BRD4 (0.43) | HSD11B1BRD4 | |
| SCHEMBL6998947 | 0.77 | BRD4 (0.54) | HSD11B1BRD4 | |
| SCHEMBL6989278 | 0.77 | PTGS1 (0.52) | HSD11B1BRD4 | |
| SCHEMBL6991232 | 0.77 | BRD4 (0.57) | HSD11B1BRD4 | |
| SCHEMBL6998152 | 0.76 | KDM4E (0.44) | HSD11B1BRD4 | |
| SCHEMBL6996631 | 0.76 | KDM4E (0.44) | HSD11B1BRD4 | |
| Hydrochloric Acid SCHEMBL8015300 | 0.74 | KDM4E (0.43) | HSD11B1BRD4 | |
| SCHEMBL24263871 | 0.73 | BRD4 (0.94) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921119-B1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0921119-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-09 | — | — | EP | disclosed |