Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6990749 | 0.99 | L3MBTL1 (0.44) | L3MBTL1PARP1PRMT5WDR77HPGD | |
| SCHEMBL6993345 | 0.89 | PARP1 (0.42) | PARP1HPGDSMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL6996685 | 0.88 | PARP1 (0.41) | PARP1HPGDSMN1; SMN2POLB | |
| SCHEMBL7002470 | 0.85 | PARP1 (0.42) | PARP1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6998857 | 0.85 | MEN1 (0.44) | PARP1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6996665 | 0.85 | HTT (0.39) | L3MBTL1PARP1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6999676 | 0.85 | PARP1 (0.43) | PARP1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL7000763 | 0.85 | PARP1 (0.43) | PARP1HPGDSMN1; SMN2ROCK1POLB | |
| Hydrochloric Acid SCHEMBL6996848 | 0.84 | PARP1 (0.41) | PARP1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL6998295 | 0.84 | HTT (0.41) | L3MBTL1PARP1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |