Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6996685 | 0.99 | PARP1 (0.41) | PARP1SMN1; SMN2TP53POLBPLK1 | |
| SCHEMBL7002470 | 0.89 | PARP1 (0.42) | PARP1CHRM2LMNA | |
| SCHEMBL6993016 | 0.89 | L3MBTL1 (0.45) | PARP1SMN1; SMN2POLBHPGD | |
| SCHEMBL6996665 | 0.88 | HTT (0.39) | PARP1SMN1; SMN2TP53POLBMEN1 | |
| Hydrochloric Acid SCHEMBL7000763 | 0.88 | PARP1 (0.43) | PARP1SMN1; SMN2TP53POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL6999676 | 0.88 | PARP1 (0.43) | PARP1SMN1; SMN2TP53POLBMEN1 | |
| Hydrochloric Acid SCHEMBL6996848 | 0.88 | PARP1 (0.41) | PARP1CHRM2LMNA | |
| Hydrochloric Acid SCHEMBL6990749 | 0.88 | L3MBTL1 (0.44) | PARP1SMN1; SMN2POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6998295 | 0.87 | HTT (0.41) | PARP1SMN1; SMN2TP53POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7713373 | 0.87 | PARP1 (0.53) | PARP1SMN1; SMN2TP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |