Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6998295 | 0.99 | HTT (0.41) | HTTPOLBPARP1MEN1KMT2A | |
| SCHEMBL6993345 | 0.88 | PARP1 (0.42) | HTTPOLBPARP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6996685 | 0.87 | PARP1 (0.41) | HTTPOLBPARP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6998857 | 0.87 | MEN1 (0.44) | HTTPOLBPARP1MEN1KMT2A | |
| SCHEMBL7002470 | 0.85 | PARP1 (0.42) | PARP1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6993016 | 0.85 | L3MBTL1 (0.45) | POLBPARP1SMN1; SMN2CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6996848 | 0.84 | PARP1 (0.41) | PARP1LMNACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6990749 | 0.84 | L3MBTL1 (0.44) | POLBPARP1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6999676 | 0.80 | PARP1 (0.43) | POLBPARP1MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL7000763 | 0.80 | PARP1 (0.43) | HTTPOLBPARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |