Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999796 | 0.90 | PTGS2 (0.39) | PGRPTGS1PTGS2 | |
| SCHEMBL6993481 | 0.88 | NOTUM (0.36) | PGR | |
| SCHEMBL7003700 | 0.85 | PGR (0.37) | PGRRXRAPTGS1PTGS2 | |
| SCHEMBL6995348 | 0.85 | RXRA (0.42) | RXRARXRBRXRG | |
| SCHEMBL6994647 | 0.84 | PTGS1 (0.49) | PGRPTGS1PTGS2 | |
| SCHEMBL6999359 | 0.84 | PGR (0.44) | PGRPTGS1PTGS2 | |
| SCHEMBL7001802 | 0.83 | KIF11 (0.43) | PGRPTGS1PTGS2 | |
| SCHEMBL6996376 | 0.82 | PTGS2 (0.38) | PGRPTGS1PTGS2 | |
| SCHEMBL6997285 | 0.81 | PTGS2 (0.47) | PGRPTGS1PTGS2 | |
| SCHEMBL6994363 | 0.78 | PDE3B (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |