Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | INMT | O95050 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989668 | 0.65 | KDM4E (0.49) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1164480 | 0.61 | SMN1; SMN2 (0.47) | MAPTALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL6989880 | 0.61 | TBXAS1 (0.39) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7973903 | 0.61 | ALDH1A1 (0.36) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7000119 | 0.61 | NOTUM (0.39) | MAPTKDM4EALDH1A1KMT2AHSD17B10 | |
| SCHEMBL18296710 | 0.60 | DAO (0.36) | MAPTALDH1A1 | |
| SCHEMBL20881146 | 0.59 | CA1 (0.40) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL24795887 | 0.59 | DRD2 (0.47) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL25365345 | 0.59 | DAO (0.35) | — | |
| SCHEMBL18296623 | 0.59 | DAO (0.35) | MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |