Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6991885 | 0.82 | ALOX15 (0.56) | ALOX15TSHRKMT2AALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6995285 | 0.78 | ALOX15 (0.52) | ALOX15TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL6992104 | 0.78 | ALDH1A1 (0.45) | TSHRKMT2AALDH1A1HSD17B10GAA | |
| SCHEMBL8038844 | 0.71 | ACHE (0.34) | GAA | |
| SCHEMBL6996979 | 0.70 | NPSR1 (0.55) | KMT2AALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL6996186 | 0.67 | GSK3B (0.52) | TSHRKMT2AALDH1A1POLBMEN1 | |
| SCHEMBL179086 | 0.66 | SMN1; SMN2 (0.77) | KMT2AALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL7440325 | 0.65 | KMT2A (0.75) | TSHRKMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL29975649 | 0.65 | ALDH1A1 (0.74) | KMT2AALDH1A1KDM4EGAAPOLB | |
| SCHEMBL28366072 | 0.65 | ALDH1A1 (0.74) | KMT2AALDH1A1KDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |