Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | EDNRA | P25101 | 3/20 | 0.34 |
| ▸ | OGA | O60502 | 2/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994787 | 0.71 | ALOX15 (0.58) | GAA | |
| SCHEMBL6992104 | 0.71 | ALDH1A1 (0.45) | GAAHTT | |
| SCHEMBL7440321 | 0.66 | GAA (0.49) | ACHEEDNRAOGAGAAHTT | |
| SCHEMBL6992010 | 0.60 | ALDH1A1 (0.42) | GAA | |
| SCHEMBL7289763 | 0.60 | EDNRA (0.51) | EDNRA | |
| SCHEMBL5717640 | 0.60 | PTGS2 (0.59) | EDNRAOGA | |
| SCHEMBL6991108 | 0.60 | EDNRA (0.51) | EDNRA | |
| SCHEMBL21632377 | 0.58 | MAPK9 (0.55) | ACHEEDNRA | |
| SCHEMBL1168388 | 0.57 | ACHE (0.60) | ACHEOGAHTT | |
| SCHEMBL2047538 | 0.57 | ACHE (0.56) | ACHEEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |