Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26419673 | 0.85 | KDM4C (0.39) | IDO1KDM4C | |
| SCHEMBL8481056 | 0.80 | HSD11B1 (0.39) | KDM4C | |
| SCHEMBL8377336 | 0.80 | SLC6A4 (0.38) | IDO1 | |
| SCHEMBL12004605 | 0.78 | GID4 (0.35) | KDM4C | |
| SCHEMBL13518963 | 0.78 | GID4 (0.35) | KDM4C | |
| SCHEMBL10058425 | 0.78 | KDM4C (0.31) | KDM4C | |
| SCHEMBL376248 | 0.78 | IDO1 (0.70) | IDO1PDPK1GPR84 | |
| SCHEMBL8382519 | 0.77 | HSD11B1 (0.33) | — | |
| SCHEMBL30789930 | 0.77 | HSD11B1 (0.35) | — | |
| SCHEMBL31511367 | 0.77 | HSD11B1 (0.37) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317459-A1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | AstraZeneca AB (SE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020530-A1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |