Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517535 | 0.93 | HTR2A (0.37) | SLC6A4HTR2AHTR2CHTR2BHSD11B1 | |
| SCHEMBL8481056 | 0.89 | HSD11B1 (0.39) | SLC6A4HSD11B1 | |
| SCHEMBL8382519 | 0.81 | HSD11B1 (0.33) | HSD11B1HPGD | |
| SCHEMBL6994885 | 0.80 | IDO1 (0.50) | IDO1 | |
| SCHEMBL18153009 | 0.76 | KDM4C (0.34) | — | |
| SCHEMBL3519977 | 0.74 | ALDH1A1 (0.34) | HSD11B1HPGD | |
| SCHEMBL12004605 | 0.74 | GID4 (0.35) | HSD11B1 | |
| SCHEMBL13518963 | 0.74 | GID4 (0.35) | HSD11B1 | |
| SCHEMBL15779251 | 0.74 | ESR2 (0.38) | — | |
| SCHEMBL31511367 | 0.73 | HSD11B1 (0.37) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| CN-1042637-C | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | CN | disclosed |
| US-5830873-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| CN-1121925-A | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1996-05-08 | — | — | CN | disclosed |
| EP-0684254-A1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |