Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | HTR2B | P41595 | 6/20 | 0.37 |
| ▸ | HTR1A | P08908 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 6/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 6/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159540 | 0.90 | HTR2A (0.36) | HTR2AHTR2CHTR2BNOTUMSRD5A1 | |
| SCHEMBL6157563 | 0.88 | HTR2A (0.36) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL6968163 | 0.86 | DRD1 (0.39) | HTR2AHTR2CHTR2BDRD3DRD2 | |
| SCHEMBL7000740 | 0.85 | DRD1 (0.39) | — | |
| SCHEMBL6995013 | 0.85 | DRD1 (0.39) | — | |
| SCHEMBL6957781 | 0.85 | DRD1 (0.39) | — | |
| SCHEMBL6956621 | 0.83 | MAOA (0.48) | DRD3DRD2 | |
| SCHEMBL7823470 | 0.82 | DRD2 (0.35) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL6160361 | 0.81 | ESR1 (0.34) | NOTUMSRD5A1 | |
| Hydrochloric Acid SCHEMBL6157964 | 0.81 | KCNH3 (0.36) | HTR2AHTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2005-10-26 | — | — | EP | disclosed |
| CN-1159312-C | Novel poyrimidine derivatives and process for preparation thereof | ������������ʽ���� | 2004-07-28 | — | — | CN | disclosed |
| US-6545008-B1 | Inhibitory activity against gastric acid secretion | YUHAN CORPORATION (KR) | 2003-04-08 | — | — | US | disclosed |
| CN-1326453-A | Novel poyrimidine derivatives and process for preparation thereof | YUHAN CORP (KR) | 2001-12-12 | — | — | CN | disclosed |
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |