SCHEMBL6574344

SCHEMBL6574344

O=C(Oc1ccccc1)c1ccc2cc(O)c(C(=O)Oc3ccccc3)cc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.57
HPGD P15428 2/20 0.56
ALOX15 P16050 2/20 0.56
HSD17B10 Q99714 2/20 0.56
MAPT P10636 6/20 0.55
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
CHRM1 P11229 1/20 0.55
TBXA2R P21731 1/20 0.55
SLC6A2 P23975 1/20 0.55
PDE4A P27815 1/20 0.55
ADRA1A P35348 1/20 0.55
KDR P35968 1/20 0.55
SLC6A3 Q01959 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
KDM4E B2RXH2 3/20 0.51
MAPK1 P28482 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7158949 0.93 MAPT (0.63) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL7121986 0.87 MAPT (0.57) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL72201 0.87 MAPT (0.62) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL1098951 0.87 HPGD (0.67) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL69953 0.87 MAPT (0.62) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL11798342 0.85 HPGD (0.66) NSD2HPGDALOX15HSD17B10MAPT
Methyl Anthranilate SCHEMBL8507224 0.85 ALDH1A1 (0.52) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL28008944 0.85 NSD2 (0.54) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL418527 0.83 MAPT (0.68) NSD2HPGDALOX15HSD17B10MAPT
SCHEMBL6054705 0.82 KMT2A (0.62) NSD2MAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881267-B1 AZO COMPOUNDS AND PROCESS FOR PREPARING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 2004-04-28 EP disclosed
US-5973126-A REACTING A 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID, AN AMIDE, OR AN ESTER THEREOF OR DERIVATIVES WITH A DIAZOTIZED AROMATIC PRIMARY AMINE; WATER RESISTANCE, CHEMICAL RESISTANCE AND SOLVENT RESISTANCE. KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-10-26 US disclosed
US-5965715-A Bisazo compounds and process for the preparation thereof KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-10-12 US disclosed
EP-0881267-A1 AZO COMPOUNDS AND PROCESS FOR PREPARING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1998-12-02 EP disclosed