Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945602 | 0.87 | ALDH1A1 (0.48) | CYP1A2PTGS2CYP1A1CYP1B1KMT2A | |
| SCHEMBL643649 | 0.82 | CYP1A2 (0.62) | CYP1A2PTGS2CYP1A1CYP1B1ALOX5 | |
| SCHEMBL900803 | 0.80 | CYP1A2 (0.61) | CYP1A2PTGS2CYP1A1CYP1B1TUBB4A | |
| SCHEMBL10044607 | 0.79 | CYP1A2 (0.44) | CYP1A2PTGS2ALOX5TUBB1ALDH1A1 | |
| SCHEMBL686849 | 0.79 | CYP1A2 (0.64) | CYP1A2PTGS2CYP1A1CYP1B1TUBB4A | |
| SCHEMBL13067787 | 0.79 | ACHE (0.64) | CYP1A2PTGS2TUBB1MEN1KMT2A | |
| SCHEMBL10044604 | 0.79 | CYP1A2 (0.46) | CYP1A2ALDH1A1CYP3A4TAAR1HSD17B10 | |
| SCHEMBL10044449 | 0.79 | DHFR (0.43) | CYP1A2PTGS2ALDH1A1CYP3A4HTR2A | |
| SCHEMBL13067433 | 0.79 | CYP1A2 (0.46) | CYP1A2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL14655675 | 0.79 | CYP1A2 (1.00) | CYP1A2TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052420-A1 | METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES | MERCK SERONO S.A. GENEVA (CH) | 2012-04-26 | — | — | WO | disclosed |
| US-20100285407-A1 | Composition for forming a silicon-containing antireflection film, substrate having the silicon-containing antireflection film from the composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-11 | — | — | US | disclosed |