Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7954259 | 0.99 | KDM4E (0.46) | KDM4EALDH1A1GLAHTTGAA | |
| SCHEMBL6996474 | 0.93 | KDM4E (0.46) | KDM4EALDH1A1GLAHTTGAA | |
| Hydrochloric Acid SCHEMBL7945151 | 0.92 | KDM4E (0.45) | KDM4EALDH1A1GLAHTTGAA | |
| SCHEMBL6993372 | 0.91 | ALDH1A1 (0.48) | KDM4EALDH1A1GLAHTTTSHR | |
| SCHEMBL6998552 | 0.90 | HRH3 (0.43) | KDM4EALDH1A1GLAHTTGAA | |
| Hydrochloric Acid SCHEMBL7950497 | 0.90 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAHTTTSHR | |
| Hydrochloric Acid SCHEMBL7950618 | 0.90 | HRH3 (0.42) | KDM4EALDH1A1GLAHTTGAA | |
| SCHEMBL6991633 | 0.84 | P2RX7 (0.47) | PRMT5CCR3ACHE | |
| SCHEMBL6999548 | 0.83 | CXCR4 (0.46) | KDM4EALDH1A1GLAHTTATM | |
| Hydrochloric Acid SCHEMBL7950551 | 0.83 | P2RX7 (0.46) | PRMT5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023898-B1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | SERVIER LAB (FR) | 2003-03-12 | — | — | EP | disclosed |
| EP-1023898-A1 | Cyano-indoles as serotonine reuptake inhibitors and as 5-HT2c receptor ligands | ADIR ET COMPAGNIE (FR) | 2000-08-02 | — | — | EP | disclosed |