Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119455 | 0.89 | — | — | |
| SCHEMBL7988326 | 0.83 | ALDH1A1 (0.35) | ESR1ESR2 | |
| SCHEMBL7708028 | 0.79 | NOS3 (0.43) | — | |
| SCHEMBL7001034 | 0.72 | LMNA (0.33) | ESR1ESR2 | |
| SCHEMBL7985549 | 0.71 | MAPT (0.43) | ESR1ESR2 | |
| SCHEMBL6991828 | 0.71 | PARP1 (0.49) | — | |
| SCHEMBL6996663 | 0.70 | SLC6A4 (0.34) | — | |
| SCHEMBL6611984 | 0.69 | PARP1 (0.45) | — | |
| SCHEMBL7985616 | 0.66 | MAPT (0.47) | ESR1ESR2 | |
| SCHEMBL5670575 | 0.66 | ESR1 (0.35) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | disclosed |
| US-6365736-B1 | TREATMENT OF NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS AND FOR ACTIVITY AS NO-SYNTHASES (NOS) INHIBITORS. | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |