Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | CCNC | P24863 | 3/20 | 0.33 |
| ▸ | CDK8 | P49336 | 3/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989475 | 0.86 | TRPM8 (0.41) | MEN1KMT2APTGDR2CCNCCDK8 | |
| SCHEMBL6990917 | 0.81 | NPC1 (0.41) | MEN1KMT2APTGDR2CCNCCDK8 | |
| SCHEMBL6992723 | 0.79 | CCNC (0.49) | PTGDR2CCNCCDK8CDK19KDM4E | |
| SCHEMBL6997444 | 0.78 | EPHX1 (0.43) | MEN1KMT2AKDM4EALOX5ALDH1A1 | |
| SCHEMBL6988288 | 0.77 | CCNC (0.39) | MEN1KMT2ACCNCCDK8CDK19 | |
| SCHEMBL6988867 | 0.76 | ALDH1A1 (0.51) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL6987226 | 0.75 | CDC7 (0.53) | MEN1KMT2ATRPM8KDM4EALDH1A1 | |
| SCHEMBL6990002 | 0.74 | NPC1 (0.53) | MEN1KMT2APTGDR2CCNCCDK8 | |
| SCHEMBL7090942 | 0.74 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL8319767 | 0.72 | TSHR (0.46) | MEN1KMT2ACCNCCDK8CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931074-B1 | CONDENSED 4,5,6,7-TETRAHYDROBENZO C]THIOPHENES AS ENHANCER FOR CELL DIFFERENTIATION INDUCTION FACTOR ACTION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | EP | claimed |