Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519421 | 1.00 | ALDH1A1 (0.65) | ALDH1A1HTTMMP2MMP9KDM4E | |
| SCHEMBL6996 | 1.00 | ALDH1A1 (0.65) | ALDH1A1HTTMMP2MMP9KDM4E | |
| Water SCHEMBL28790504 | 0.98 | ALDH1A1 (0.63) | ALDH1A1HTTMMP2MMP9KDM4E | |
| SCHEMBL2977278 | 0.95 | ALDH1A1 (0.72) | ALDH1A1HTTMMP2MMP9HSD17B10 | |
| SCHEMBL1385016 | 0.95 | ALDH1A1 (0.72) | ALDH1A1HTTMMP2MMP9HSD17B10 | |
| SCHEMBL5702097 | 0.92 | ALDH1A1 (0.58) | ALDH1A1HTTMMP2MMP9KDM4E | |
| SCHEMBL5702286 | 0.92 | ALDH1A1 (0.58) | ALDH1A1HTTMMP2MMP9KDM4E | |
| SCHEMBL21519741 | 0.92 | ALDH1A1 (0.58) | ALDH1A1HTTMMP2MMP9KDM4E | |
| SCHEMBL1750430 | 0.91 | MMP2 (0.76) | ALDH1A1HTTMMP2MMP9KDM4E | |
| SCHEMBL4653160 | 0.91 | MMP2 (0.76) | ALDH1A1HTTMMP2MMP9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614201-B2 | Heterocyclic amides as modulators of TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-24 | — | — | US | claimed |
| WO-2010141805-A1 | HETEROCYCLIC AMIDES AS MODULATORS OF TRPA1 | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | claimed |
| US-7410995-B1 | N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders | GPI NIL HOLDINGS INC. (US) | 2008-08-12 | — | — | US | claimed |
| EP-0944618-B1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER IND & SANTE (FR) | 2003-09-24 | — | — | EP | claimed |
| EP-0991650-B1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER IND & SANTE (FR) | 2003-09-10 | — | — | EP | claimed |
| US-20020010205-A1 | N-linked sulfone of heterocyclic thioester hair growth compositions and uses | GPI NIL HOLDINGS, INC. | 2002-01-24 | — | — | US | claimed |
| EP-1149099-A2 | IMIDAZO[4,5-C]-PYRIDINE-4-ON-DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-10-31 | — | — | EP | claimed |
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | claimed |
| EP-1105126-A2 | SULFONAMIDES OF N-CONTAINING HETEROCYCLIC THIOESTERS FOR VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | claimed |
| EP-1085854-A1 | N-LINKED SULFONAMIDE OF HETEROCYCLIC THIOESTER HAIR GROWTH COMPOUNDS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-28 | — | — | EP | claimed |
| US-6063791-A | N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-05-16 | — | — | US | claimed |
| EP-0991650-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-04-12 | — | — | EP | claimed |
| WO-2000009107-A2 | SULFONAMIDES OF N-CONTAINING HETEROCYCLIC THIOESTERS FOR VISION AND MEMORY DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | claimed |
| WO-1999062489-A1 | N-LINKED SULFONAMIDE OF HETEROCYCLIC THIOESTER HAIR GROWTH COMPOUNDS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-0944618-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-09-29 | — | — | EP | claimed |
| EP-0925295-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-06-30 | — | — | EP | claimed |
| US-5874449-A | INHIBITORS OF IMMUNOPHILIN | GPI NIL HOLDINGS, INC. (US) | 1999-02-23 | — | — | US | claimed |
| WO-1999000387-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE COMPOUNDS, PREPARATION METHOD AND USE IN THERAPY | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-01-07 | — | — | WO | claimed |
| WO-1998024783-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-06-11 | — | — | WO | claimed |
| WO-1998003503-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-01-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010205-A1 | N-linked sulfone of heterocyclic thioester hair growth compositions and uses | ACOT7, STS, TST | ALDH1A1 1438/4885HTT 314/4885MMP2 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.