Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GHSR | Q92847 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977278 | 1.00 | ALDH1A1 (0.72) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL6997 | 0.95 | ALDH1A1 (0.65) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL23519421 | 0.95 | ALDH1A1 (0.65) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL6996 | 0.95 | ALDH1A1 (0.65) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| Water SCHEMBL28790504 | 0.94 | ALDH1A1 (0.63) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL7995082 | 0.91 | MMP2 (0.70) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL7995079 | 0.91 | MMP2 (0.70) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL5702097 | 0.90 | ALDH1A1 (0.58) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL21519741 | 0.90 | ALDH1A1 (0.58) | ALDH1A1HTTLMNAMAPTNPSR1 | |
| SCHEMBL5702286 | 0.90 | ALDH1A1 (0.58) | ALDH1A1HTTLMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4812758-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| US-7777042-B2 | N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof | AVENTIS PHARMACEUTICALS INC. (US) | 2010-08-17 | — | — | US | claimed |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | claimed |
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | claimed |
| US-20260144730-A1 | COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2026-05-28 | — | — | US | disclosed |
| US-20260083715-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2026-03-26 | — | — | US | disclosed |
| EP-4692062-A1 | NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME | Amorepacific Corporation (KR) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024205303-A1 | NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME | (주)아모레퍼시픽 | 2024-10-03 | — | — | WO | disclosed |
| US-20240270742-A1 | SUBSTITUTED AMINO ACIDS AS INTEGRIN INHIBITORS | PLIANT THERAPEUTICS INC (US) | 2024-08-15 | — | — | US | disclosed |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2022-05-12 | — | — | US | disclosed |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| CN-113195053-A | Amino acid compounds and methods of use | 普利安特治疗公司 | 2021-07-30 | — | — | CN | disclosed |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2020-04-09 | — | — | US | disclosed |
| US-7777042-B2 | N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof | AVENTIS PHARMACEUTICALS INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | disclosed |
| EP-1778637-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | Aventis Pharmaceuticals, Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144730-A1 | COMPOSITION FOR SKIN ANTI-AGING, SKIN BRIGHTENING OR SKIN REVERSE-AGING CONTAINING AMIDE-BASED COMPOUND | TYR, ATG13, ARGLU1 | ALDH1A1 1443/4885HTT 1805/4885LMNA 147/4885 |
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA1, ITGAL | ALDH1A1 1981/4885HTT 4656/4885LMNA 1922/4885 |
| US-20260083715-A1 | COMPOSITION FOR ENHANCING IMMUNITY CONTAINING AMIDE-BASED COMPOUND | ARG1, MSR1, TLR1 | ALDH1A1 3501/4885HTT 4042/4885LMNA 3265/4885 |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA1, ITGAL | ALDH1A1 1981/4885HTT 4656/4885LMNA 1922/4885 |
| US-11952376-B2 | Substituted amino acids as integrin inhibitors | ITGB6, ITGA1, ITGB1 | ALDH1A1 2168/4885HTT 4639/4885LMNA 2121/4885 |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | ITGB6, ITGA1, ITGB1 | ALDH1A1 2168/4885HTT 4639/4885LMNA 2121/4885 |
| US-20240270742-A1 | SUBSTITUTED AMINO ACIDS AS INTEGRIN INHIBITORS | ITGB6, ITGA1, ITGB1 | ALDH1A1 2168/4885HTT 4639/4885LMNA 2121/4885 |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | FKBP1A, FKBP1B, FKBP3 | ALDH1A1 3038/4885HTT 535/4885LMNA 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.