SCHEMBL699704

SCHEMBL699704

Ic1ccc(/C=C/c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.56
NFE2L2 Q16236 2/20 0.56
CYP19A1 P11511 2/20 0.56
MAOA P21397 2/20 0.56
APP P05067 2/20 0.54
RELA Q04206 3/20 0.50
TRPA1 O75762 2/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CHAT P28329 2/20 0.46
HDAC1 Q13547 1/20 0.45
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699705 1.00 MAOB (0.56) MAOBNFE2L2CYP19A1MAOAAPP
SCHEMBL10120088 0.90 MAOB (0.70) MAOBNFE2L2CYP19A1MAOAAPP
SCHEMBL699783 0.88 APP (0.64) MAOBNFE2L2CYP19A1MAOAAPP
SCHEMBL699782 0.88 APP (0.64) MAOBNFE2L2CYP19A1MAOAAPP
SCHEMBL83955 0.85 NFE2L2 (0.72) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL44504 0.85 NFE2L2 (0.72) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL14166008 0.85 NFE2L2 (0.72) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL11547655 0.85 NFE2L2 (0.72) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL22164138 0.85 NFE2L2 (0.72) MAOBNFE2L2CYP19A1MAOARELA
SCHEMBL11547654 0.85 NFE2L2 (0.72) MAOBNFE2L2CYP19A1MAOARELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 US disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
CN-102005220-B Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC 2015-06-03 CN disclosed
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 US disclosed
US-8507153-B2 Compositions, optical data storage media and methods for using the optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-08-13 US disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 EP disclosed
US-20110053054-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
US-20040005649-A1 Anti-stilbene antibodies SCRIPPS RESEARCH INSTITUTE, THE 2004-01-08 US disclosed
WO-2002022629-A1 ANTI-STILBENE ANTIBODIES THE SCRIPPS RESEARCH INSTITUTE (US) 2002-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAOB 739/4885NFE2L2 253/4885CYP19A1 1811/4885
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR MAOB 157/4885NFE2L2 102/4885CYP19A1 504/4885
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR MAOB 157/4885NFE2L2 102/4885CYP19A1 504/4885
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAOB 739/4885NFE2L2 253/4885CYP19A1 1811/4885
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT MAOB 3769/4885NFE2L2 4162/4885CYP19A1 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.