Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048843 | 0.85 | ALDH1A1 (0.50) | MAOBMAOAAPPDAOALDH1A1 | |
| SCHEMBL27224963 | 0.82 | MEN1 (0.49) | MAOBMAOAALDH1A1LMNAMAPT | |
| SCHEMBL19255108 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTSMN1; SMN2ATM | |
| SCHEMBL7002851 | 0.80 | KMT2A (0.50) | MAOBMAOAAPPALDH1A1LMNA | |
| SCHEMBL28070731 | 0.78 | APP (0.60) | MAOBMAOAAPPALDH1A1LMNA | |
| SCHEMBL572373 | 0.77 | PTGES (0.55) | MAOBAPPLMNAMAPTSMN1; SMN2 | |
| SCHEMBL29445159 | 0.77 | TDP1 (0.58) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL6520 | 0.77 | TDP1 (0.58) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL31011691 | 0.77 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTNCOA1NCOA3 | |
| SCHEMBL6997741 | 0.77 | MAOB (0.56) | MAOBMAOAAPPDAOLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086078-B1 | NEUROPEPTIDE Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-02-05 | — | — | EP | disclosed |
| US-6329395-B1 | UREA DERIVATIVES FOR TREATING AN EATING DISORDER OR DIABETES COMPRISING ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF CLAIM 1 TO A MAMMAL | SCHERING CORPORATION | 2001-12-11 | — | — | US | disclosed |
| EP-1086078-A1 | NEUROPEPTIDE Y5 RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064394-A1 | NEUROPEPTIDE Y5 RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 1999-12-16 | — | — | WO | disclosed |