SCHEMBL699740

SCHEMBL699740

C=Cc1ccccc1C(=O)c1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
MAPT P10636 2/20 0.56
MAPK1 P28482 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HSD17B10 Q99714 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
EGFR P00533 1/20 0.56
TP53 P04637 1/20 0.56
CYP3A4 P08684 1/20 0.56
PKM P14618 1/20 0.56
HPGD P15428 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
JAK1 P23458 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
HSD17B14 Q9BPX1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31727764 0.79 AKR1C3 (0.55) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL173243 0.79 AKR1C3 (0.55) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL38132 0.78 ALDH1A1 (0.44) MEN1KMT2AMAPTSMN1; SMN2HSD17B10
SCHEMBL30250451 0.76 CES2 (0.74) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL29613672 0.76 CES2 (0.74) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL941698 0.76 CES2 (0.74) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL19971523 0.76 KMT2A (0.60) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL18535747 0.76 LIG1 (0.61) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL29709993 0.76 LIG1 (0.61) MEN1KMT2AMAPTMAPK1SMN1; SMN2
SCHEMBL7828608 0.76 CDC25B (0.70) MEN1KMT2AMAPTMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778568-B2 Optical data storage media and methods for using the same GENERAL ELECTRIC COMPANY (US) 2014-07-15 US disclosed
EP-2466582-B1 Optical Data Storage Media And Methods For Using The Same GEN ELECTRIC (US) 2014-02-26 EP disclosed
EP-2423917-B1 Use of chemically bonded dyes in holographic data storage media GEN ELECTRIC (US) 2013-08-07 EP disclosed
US-8343608-B2 Use of appended dyes in optical data storage media GENERAL ELECTRIC COMPANY (US) 2013-01-01 US disclosed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 EP disclosed
EP-2290408-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-08-15 EP disclosed
EP-2466582-A1 Optical Data Storage Media And Methods For Using The Same General Electric Company (US) 2012-06-20 EP disclosed
US-20120147724-A1 OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2012-06-14 US disclosed
US-8178261-B2 Optical data storage media and methods for using the same GENERAL ELECTRIC COMPANY (US) 2012-05-15 US disclosed
US-20120052232-A1 USE OF APPENDED DYES IN OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2012-03-01 US disclosed
EP-2423917-A2 Use of chemically bonded dyes in holographic data storage media General Electric Company (US) 2012-02-29 EP disclosed
US-20110081602-A1 OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2011-04-07 US disclosed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 US disclosed