SCHEMBL38132

SCHEMBL38132

C=Cc1ccccc1C(=O)c1ccccc1C=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
CYP3A4 P08684 1/20 0.41
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALOX15 P16050 1/20 0.40
TP53 P04637 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
BCHE P06276 1/20 0.38
GUSB P08236 1/20 0.38
AKT1 P31749 1/20 0.38
GSR P00390 1/20 0.37
AKR1C3 P42330 1/20 0.37
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CDC25B P30305 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4622093 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15AKR1C3LMNA
SCHEMBL31588660 0.88 MAPT (0.44) ALDH1A1TP53GAAMAPTMEN1
SCHEMBL7932918 0.88 ALDH1A1 (0.36) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL31727764 0.87 AKR1C3 (0.55) ALDH1A1GAAMAPTAKT1AKR1C3
SCHEMBL173243 0.87 AKR1C3 (0.55) ALDH1A1GAAMAPTAKT1AKR1C3
SCHEMBL6693580 0.86 CES2 (0.44) ALDH1A1CYP3A4TSHRALOX15BCHE
SCHEMBL31100 0.84 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2ALOX15MAPTAKT1
SCHEMBL30259301 0.84 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2ALOX15MAPTAKT1
SCHEMBL985923 0.84 ALDH1A1 (0.43) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
Vinyl Chloride SCHEMBL28345010 0.82 AKR1C3 (0.50) ALDH1A1GAAMAPTAKT1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599752-A Compositions and methods for selective chemical mechanical polishing of oxides CMC材料股份有限公司 2022-06-07 CN claimed
US-20130202531-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. 2013-08-08 US claimed
EP-2382080-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS Indicator Systems International, Inc. (US) 2011-11-02 EP claimed
US-20110042344-A1 POLYMERIC INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. 2011-02-24 US claimed
US-20100196636-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. 2010-08-05 US claimed
WO-2010085755-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2010-07-29 WO claimed
US-7749531-B2 Apparatus and method for detecting bacterial growth beneath a wound dressing INDICATOR SYSTEMS INTERNATIONAL (US) 2010-07-06 US claimed
WO-2009061831-A1 POLYMERIC INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2009-05-14 WO claimed
EP-1893147-A2 APPARATUS AND METHOD FOR DETECTING BACTERIAL GROWTH BENEATH A WOUND DRESSING Indicator Systems International, Inc. (US) 2008-03-05 EP claimed
US-20070003606-A1 Apparatus and method for detecting bacterial growth beneath a wound dressing OSRAM SYLVANIA INC. 2007-01-04 US claimed
WO-2006133430-A2 APPARATUS AND METHOD FOR DETECTING BACTERIAL GROWTH BENEATH A WOUND DRESSING INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2006-12-14 WO claimed
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP claimed
US-6149952-A Method for determining deleterious bacterial growth in packaged food utilizing hydrophilic polymers Stoltenberg, Herbert W. (US) 2000-11-21 US claimed
WO-1999059431-A1 METHOD FOR DETERMINING DELETERIOUS BACTERIAL GROWTH IN PACKAGED FOOD UTILIZING HYDROPHILIC POLYMERS THOMAS J. HORAN FAMILY TRUST (US) 1999-11-25 WO claimed
CN-117501421-A Structure containing underlying barrier metal and solder layer 石原化学株式会社 2024-02-02 CN disclosed
CN-108997215-B Preparation method of 1,2,3, 4-tetrahydroisoquinoline derivative 武汉大学 2020-05-22 CN disclosed
CN-110577483-B Green synthesis method of 3, 3-disubstituted-2-indolone 海南医学院 2020-05-12 CN disclosed
US-4065430-A Functional group containing polymer and method of preparing the same FUJI PHOTO FILM CO., LTD. (JA) 1977-12-27 US disclosed
US-3984599-A MINERAL OIL, WAXES, WAX CRYSTAL MODIFIER EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-10-05 US disclosed
US-3933885-A Cinnamylideneacetic acid esters FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100196636-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS PGLS, MGAM, G6PD ALDH1A1 244/4885CYP3A4 311/4885TSHR 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.