Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997445 | 1.00 | HTR6 (0.36) | HTR6 | |
| SCHEMBL7008847 | 0.77 | SLC6A4 (0.51) | HTR6 | |
| SCHEMBL6996253 | 0.70 | SLC6A4 (0.56) | HTR6 | |
| SCHEMBL6996256 | 0.70 | SLC6A4 (0.56) | HTR6 | |
| SCHEMBL7006768 | 0.69 | HTR6 (0.40) | HTR6 | |
| SCHEMBL7007896 | 0.69 | HTR6 (0.51) | HTR6 | |
| SCHEMBL7007900 | 0.69 | HTR6 (0.51) | HTR6 | |
| SCHEMBL7010544 | 0.67 | HTR6 (0.44) | HTR6 | |
| SCHEMBL7012792 | 0.67 | HTR6 (0.44) | HTR6 | |
| SCHEMBL8385371 | 0.67 | HTR6 (0.42) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562809-B1 | Contraction of coronary arteries may be mediated by its stimulation of the 5-HT1B (formerly 5-HT1D beta); compounds selective for a 5-HT1D receptor | NPS ALLELIX CORP. (CA) | 2003-05-13 | — | — | US | disclosed |
| EP-1114049-B1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS ALLELIX CORP (CA) | 2003-03-19 | — | — | EP | disclosed |
| EP-1114049-A1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS | NPS Allelix Corp. (CA) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017198-A1 | 3-BICYCLOINDOLE COMPOUNDS AS 5-HT1D LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-03-30 | — | — | WO | disclosed |