Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001508 | 0.83 | CA12 (0.51) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL6993208 | 0.82 | CA12 (0.58) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL3558164 | 0.79 | CA12 (0.78) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL1177272 | 0.76 | CA12 (0.58) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL3563271 | 0.76 | CA12 (0.56) | CA12CA9CA2RECQLALDH1A1 | |
| SCHEMBL28414154 | 0.74 | CA12 (0.71) | CA12CA9CA2ALDH1A1PTGS2 | |
| SCHEMBL6990241 | 0.74 | CA12 (0.40) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL5358792 | 0.74 | CA12 (0.62) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL6996060 | 0.74 | CA12 (0.42) | CA12CA9CA2RECQLCREBBP | |
| SCHEMBL7004177 | 0.74 | CA12 (0.44) | CA12CA9CA2RECQLCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109785-B1 | INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF MALIGNANT AND OTHER DISEASES CAUSED BY PATHOLOGICAL CELL PROLIFERATION | ZENTARIS AG (DE) | 2003-01-02 | — | — | EP | disclosed |