Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.38 |
| ▸ | PRKCG | P05129 | 5/20 | 0.38 |
| ▸ | PRKCB | P05771 | 5/20 | 0.38 |
| ▸ | PRKCA | P17252 | 5/20 | 0.38 |
| ▸ | PRKCH | P24723 | 5/20 | 0.38 |
| ▸ | PRKCI | P41743 | 5/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | PRKACG | P22612 | 2/20 | 0.38 |
| ▸ | PRKACB | P22694 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996060 | 0.90 | CA12 (0.42) | CA12CA9CA2PRKD3PRKCG | |
| SCHEMBL6990241 | 0.88 | CA12 (0.40) | CA12CA9CA2CREBBPRECQL | |
| SCHEMBL7001508 | 0.78 | CA12 (0.51) | CA12CA9CA2CREBBPRECQL | |
| SCHEMBL6997478 | 0.74 | CA12 (0.60) | CA12CA9CA2CREBBPRECQL | |
| SCHEMBL6993208 | 0.70 | CA12 (0.58) | CA12CA9CA2CREBBPRECQL | |
| SCHEMBL14577242 | 0.70 | CA12 (0.49) | CA12CA9CA2RECQLALDH1A1 | |
| SCHEMBL7003019 | 0.69 | KDR (0.46) | CA12CA9CA2PRKD3PRKCG | |
| SCHEMBL6999579 | 0.66 | HEXA (0.49) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3558164 | 0.66 | CA12 (0.78) | CA12CA9CA2CREBBPRECQL | |
| SCHEMBL7506853 | 0.64 | CHEK1 (0.53) | CA12CA9CA2PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109785-B1 | INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF MALIGNANT AND OTHER DISEASES CAUSED BY PATHOLOGICAL CELL PROLIFERATION | ZENTARIS AG (DE) | 2003-01-02 | — | — | EP | disclosed |