Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.62 |
| ▸ | CA9 | Q16790 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | ACLY | P53396 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558164 | 0.84 | CA12 (0.78) | CA12CA9CA2ACLYALDH1A1 | |
| SCHEMBL5349374 | 0.76 | CA12 (0.62) | CA12CA9CA2ACLYALDH1A1 | |
| SCHEMBL1177272 | 0.75 | CA12 (0.58) | CA12CA9CA2ACLYALDH1A1 | |
| SCHEMBL28523450 | 0.75 | CA12 (0.69) | CA12CA9CA2ACLYCXCL8 | |
| SCHEMBL28017014 | 0.75 | CA12 (0.69) | CA12CA9CA2ACLYALDH1A1 | |
| SCHEMBL1156079 | 0.74 | ERN1 (0.37) | CA12CA9CA2ALDH1A1MEN1 | |
| SCHEMBL12496998 | 0.74 | CNR1 (0.54) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL6997478 | 0.74 | CA12 (0.60) | CA12CA9CA2ACLYALDH1A1 | |
| SCHEMBL3433282 | 0.74 | CA12 (0.60) | CA12CA9CA2ACLYALDH1A1 | |
| SCHEMBL1156096 | 0.74 | PTGDR2 (0.39) | CA12CA9CA2ALDH1A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100396678-C | Synthesis and use of indole analogues of 1-benzyl-3- (5 '-hydroxymethyl-2' -furyl) indazole | IND TECH RES INST (CN) | 2008-06-25 | — | — | CN | disclosed |
| US-7176230-B2 | Synthesis of indole analogs of 1-benzyl-3-(5′-hydroxymethyl-2′-furyl) indazole (YC-1) as anti-platelet agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2007-02-13 | — | — | US | disclosed |
| CN-1827616-A | Synthesis and use of indole analogues of 1-benzyl-3- (5 '-hydroxymethyl-2' -furyl) indazole | IND TECH RES INST (CN) | 2006-09-06 | — | — | CN | disclosed |
| US-20060106041-A1 | Synthesis of indole analogs of 1-benzyl-3-(5'-hydroxymethy 1-2' -furyl) indazole (YC-1) as anti-platelet agents | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106041-A1 | Synthesis of indole analogs of 1-benzyl-3-(5'-hydroxymethy 1-2' -furyl) indazole (YC-1) as anti-platelet agents | PFKP, HMOX1, TPH1 | CA12 4872/4885CA9 4463/4885CA2 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.