SCHEMBL699759

SCHEMBL699759

Nc1cccc(Cc2cccc(N)c2Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.44
TSHR P16473 3/20 0.40
TAAR1 Q96RJ0 2/20 0.40
ALDH1A1 P00352 3/20 0.39
NR4A2 P43354 1/20 0.39
IDO1 P14902 3/20 0.39
CYP3A4 P08684 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PIK3CA P42336 1/20 0.36
HSP90AA1 P07900 1/20 0.34
HSPA5 P11021 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL1818621 0.95 PNMT (0.41) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL5591177 0.85 PNMT (0.62) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL9851031 0.85 HTR2A (0.47) PNMTTSHRCYP3A4HPGDHSD17B10
SCHEMBL8145738 0.83 TSHR (0.41) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL15474463 0.82 CYP3A4 (0.67) PNMTTSHRTAAR1ALDH1A1IDO1
SCHEMBL1547908 0.81 PNMT (0.41) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL29944235 0.81 PNMT (0.41) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL3789673 0.81 GABRA1 (0.44) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL27396074 0.81 PNMT (0.57) PNMTTSHRTAAR1ALDH1A1NR4A2
SCHEMBL1670544 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-3985777-B1 SECONDARY BATTERY LG ENERGY SOLUTION LTD (KR) 2025-09-03 EP claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
US-20250243313-A1 POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-31 US claimed
US-20250230274-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 US claimed
WO-2025149744-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 WO claimed
CN-120092033-A Novel polyurethane or polyurethane-urea compositions with enhanced low temperature properties 英格维蒂英国有限公司 2025-06-03 CN claimed
US-12234316-B2 Acrylate oligomer and preparation method and application method thereof ZHEJIANG UNIVERSITY (CN) 2025-02-25 US claimed
CN-119391140-A Modified epoxy resin and preparation method and application thereof 金安国纪科技(安徽)有限公司 2025-02-07 CN claimed
CN-119100655-A Elastic polyurea mortar and preparation method thereof 中国电建集团西北勘测设计研究院有限公司 2024-12-10 CN claimed
EP-1609905-A1 Papermaking machine belt and method for manufacturing a papermaking machine belt ICHIKAWA CO.,LTD. (JP) 2005-12-28 EP claimed
EP-0955317-B1 Grafted maleimide-styrene-g-polypropylene copolymers used in rubber compounds for increasing hysteresis BRIDGESTONE CORP (JP) 2004-08-04 EP claimed
EP-0352550-B1 Resin composition for laminate MITSUBISHI ELECTRIC CORP (JP) 1996-03-27 EP claimed
EP-0284289-B1 POLYURETHANE RESIN COMPOSITION HODOGAYA CHEMICAL CO., LTD. (JP) 1993-01-07 EP claimed
US-5091481-A Heat resistance MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-02-25 US claimed
EP-0352550-A2 Resin composition for laminate MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1990-01-31 EP claimed
US-4602079-A Urethane elastomers prepared using a prepolymer prepared from a polyester which reacts with a chain-extending agent and/or a saturated polyester resin in which at least one of the polyesters is prepared from a dimer and/or trimer fatty acid WITCO CHEMICAL CORPORATION (US) 1986-07-22 US claimed
US-4559395-A TETRABROMOBISPHENOL A-EPICHLORAHYDRIN; FOR ELECTRICAL LAMINATES SHELL OIL COMPANY (US) 1985-12-17 US claimed
US-4554342-A Heat-curable compositions comprising an epoxy resin, an amine and a sulfonium salt SHELL OIL COMPANY (US) 1985-11-19 US claimed
US-4299932-A ADDITION-CONDENSATION COPOLYMER OF A HYDROLYSED ISOCYANATE-AMIDE-MODIFIED DIENE, POLYURETHANE, AND POLYUREA THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS PUF60, MORF4L1, C9 PNMT 2641/4885TSHR 4502/4885TAAR1 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.