Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000149 | 0.84 | OPRL1 (0.34) | GRM5CYP1A2ALDH1A1HSD17B10OPRL1 | |
| SCHEMBL6992532 | 0.82 | TRPA1 (0.32) | — | |
| SCHEMBL6998018 | 0.82 | DRD2 (0.36) | GRM5 | |
| SCHEMBL16555300 | 0.78 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL379213 | 0.78 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL16565846 | 0.78 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL6996255 | 0.78 | TRPA1 (0.33) | — | |
| SCHEMBL6617204 | 0.74 | TRPA1 (0.34) | OPRL1 | |
| SCHEMBL7229126 | 0.73 | OPRM1 (0.40) | GRM5CYP1A2ALDH1A1HSD17B10OPRL1 | |
| SCHEMBL6998787 | 0.73 | TRPA1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946553-B1 | 8-AZABICYCLO 3.2.1]OCTANE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INSECTICIDES | SYNGENTA LTD (GB) | 2003-01-29 | — | — | EP | disclosed |
| US-6174894-B1 | Bicyclic amine derivatives | ZENECA LIMITED (GB) | 2001-01-16 | — | — | US | disclosed |
| US-6093726-A | AN INSECTICIDES, ACARICIDES OR NEMATICIDES | ZENECA LIMITED (GB) | 2000-07-25 | — | — | US | disclosed |