Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631555 | 0.95 | TSPO (0.65) | TSPOADORA1ALDH1A1MAPTAPP | |
| SCHEMBL7626412 | 0.94 | MAPT (0.55) | TSPOADORA1ALDH1A1MAPTRXFP1 | |
| SCHEMBL7632526 | 0.94 | TSPO (0.54) | TSPOADORA1ALDH1A1MAPTAPP | |
| SCHEMBL7001447 | 0.86 | TSPO (0.62) | TSPOALDH1A1MAPTTP53 | |
| SCHEMBL7626011 | 0.83 | TSPO (0.64) | TSPOMAPTSMN1; SMN2TP53 | |
| SCHEMBL5702445 | 0.81 | TSPO (0.67) | TSPOMAPTTP53 | |
| SCHEMBL7002472 | 0.81 | TSPO (0.56) | TSPOALDH1A1MAPTHPGDTSHR | |
| SCHEMBL6999958 | 0.81 | TSPO (0.54) | TSPOALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL7005121 | 0.80 | MAPT (0.60) | TSPOALDH1A1MAPTAPPTSHR | |
| SCHEMBL6703839 | 0.80 | SMN1; SMN2 (0.54) | TSPOALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451795-B1 | CENTRAL NEURODEGENERATIVE DISEASES | SANOFI-SYNTHELABO (FR) | 2002-09-17 | — | — | US | disclosed |