Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | HPN | P05981 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959163 | 0.80 | MAOA (0.53) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL29448274 | 0.78 | KDM4E (0.57) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL15509594 | 0.78 | KDM4E (0.57) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL15680616 | 0.78 | KDM4E (0.46) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL24354167 | 0.77 | MAOA (0.52) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL20652853 | 0.76 | MAOA (0.50) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL4455687 | 0.75 | KDM4E (0.47) | MAPTALDH1A1HSD17B10TDP1KDR | |
| SCHEMBL1611599 | 0.75 | MAOA (0.47) | MAPTALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL32672790 | 0.75 | TDP2 (0.50) | MAPTALDH1A1HSD17B10ALOX15TDP1 | |
| SCHEMBL855553 | 0.75 | MAOA (0.47) | MAPTALDH1A1HSD17B10ALOX5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220386582-A1 | METHOD AND DEVICE TO TRAP ACARIDS | DOMOBIOS (BE) | 2022-12-08 | — | — | US | disclosed |
| CN-113413439-B | Traditional Chinese medicine formula for treating Alzheimer's disease and preparation method of compound preparation of traditional Chinese medicine formula | 中山创天生物科技有限公司 | 2022-03-29 | — | — | CN | disclosed |
| US-20210161130-A1 | COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF | DOMOBIOS (BE) | 2021-06-03 | — | — | US | disclosed |
| EP-3813530-A1 | COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF | Domobios (BE) | 2021-05-05 | — | — | EP | disclosed |
| US-20200344991-A1 | METHOD AND DEVICE TO TRAP ACARIDS | DOMOBIOS (BE) | 2020-11-05 | — | — | US | disclosed |
| EP-3253203-B1 | METHOD AND DEVICE TO TRAP ACARIDS | DOMOBIOS (BE) | 2020-10-28 | — | — | EP | disclosed |
| WO-2020162471-A1 | PYRIDONE DERIVATIVE | マルホ株式会社 | 2020-08-13 | — | — | WO | disclosed |
| US-20180027793-A1 | METHOD AND DEVICE TO TRAP ACARIDS | DOMOBIOS (BE) | 2018-02-01 | — | — | US | disclosed |
| WO-2018010332-A1 | MEDICAL USE OF 7-HYDROXY-BUTYLPHTHALIDE | 华北制药集团新药研究开发有限责任公司 | 2018-01-18 | — | — | WO | disclosed |
| US-20170273981-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | GLAXOSMITHKLINE S.P.A. (IT) | 2017-09-28 | — | — | US | disclosed |
| US-6465660-B1 | PARTICULARLY 2-HYDROXY-8,9-DIMETHOXYISOINDOLO(2,1-A)INDOL-6-ONE AND 2-HYDROXY-8,9-DIMETHOXYISOINDOLO(2,1-A)INDOL-6-ONE; TREATING A DISORDER OF THE MELATONINERGIC SYSTEM | LES LABORATOIRES SERVIER (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1241169-A1 | Isoindoloindolone derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-09-18 | — | — | EP | disclosed |
| US-5428002-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0447506-B1 | PYRIMIDINE AND TRIAZINE DERIVATIVES WITH HERBICIDAL AND PLANT GROWTH REGULATING PROPERTIES | CIBA GEIGY AG (CH) | 1994-10-26 | — | — | EP | disclosed |
| US-5332717-A | Herbicides, plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1994-07-26 | — | — | US | disclosed |
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0375560-B1 | ARYLOXYPROPANOLAMINOTETRALINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ELF SANOFI (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0447506-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES WITH HERBICIDAL AND PLANT GROWTH REGULATING PROPERTIES. | MAAG AG R (CH) | 1991-09-25 | — | — | EP | disclosed |
| WO-1991005781-A1 | PYRIMIDINE AND TRIAZINE DERIVATIVES WITH HERBICIDAL AND PLANT GROWTH REGULATING PROPERTIES | DR. R. MAAG AG (CH) | 1991-05-02 | — | — | WO | disclosed |
| EP-0375560-A1 | Aryloxypropanolaminotetralines, process for their preparation and pharmaceutical compositions containing same | ELF SANOFI (FR) | 1990-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273981-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNA3, KCND3, KCNN3 | MAPT 3971/4885ALDH1A1 1789/4885HSD17B10 2091/4885 |
| US-20210161130-A1 | COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF | ACAT1, ATL3, NISCH | MAPT 215/4885ALDH1A1 2159/4885HSD17B10 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.