Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369262 | 1.00 | CYP1A2 (0.56) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL6816267 | 0.86 | GRIN2D (0.49) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL29156239 | 0.83 | CYP1A2 (0.53) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL29474148 | 0.83 | CYP1A2 (0.53) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL6814356 | 0.81 | GPR35 (0.46) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17378984 | 0.81 | ALDH1A1 (0.73) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL19931897 | 0.81 | TDP1 (0.47) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL30771104 | 0.79 | GRIN2D (0.43) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL30771217 | 0.79 | MAPT (0.44) | CYP1A2ALDH1A1TDP1TSHRGRIN2D | |
| SCHEMBL5041177 | 0.79 | CYP1A2 (0.59) | CYP1A2ALDH1A1TDP1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561563-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026129-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11491091-B2 | Cooling product | SYMRISE AG (DE) | 2022-11-08 | — | — | US | disclosed |
| CN-114007734-A | Method for preparing capsules | 宝洁公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113660926-A | Capsule | 宝洁公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113631695-A | Capsule | 宝洁公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | disclosed |
| EP-3434330-A1 | A METHOD FOR ENHANCING THE COOLING EFFECT OF A COOLING COMPOUND | Symrise AG (DE) | 2019-01-30 | — | — | EP | disclosed |
| EP-2741731-B1 | ENCAPSULATES | PROCTER & GAMBLE (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-2803666-B1 | Cyclic acetals and ketals and their use as fragrance compounds | SYMRISE AG (DE) | 2016-04-27 | — | — | EP | disclosed |
| EP-2421815-B1 | ACETALS AS PERFUMING INGREDIENTS | FIRMENICH & CIE (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2568035-A1 | Perfume mixtures containing certain isolongifolenyl methyl ethers | Symrise AG (DE) | 2013-03-13 | — | — | EP | disclosed |
| EP-2287158-B1 | Ambergris Odorous Substance based on 9-Methanoazuleno(5,6-d)-1,3-dioxoles | SYMRISE AG (DE) | 2012-11-14 | — | — | EP | disclosed |
| US-8236749-B2 | Acetals as perfuming ingredients | FIRMENICH SA (CH) | 2012-08-07 | — | — | US | disclosed |
| EP-2468239-A1 | Encapsulates | Procter & Gamble International Operations SA (CH) | 2012-06-27 | — | — | EP | disclosed |
| EP-2421815-A1 | ACETALS AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120010114-A1 | ACETALS AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2012-01-12 | — | — | US | disclosed |
| EP-2287158-A1 | Ambergris Odorous Substance based on 9-Methanoazuleno(5,6-d)-1,3-dioxoles | Symrise AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| WO-2010122451-A1 | ACETALS AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2010-10-28 | — | — | WO | disclosed |
| EP-2184339-A1 | Perfume mixtures containing isolongifolanol and musk | Symrise GmbH & Co. KG (DE) | 2010-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491091-B2 | Cooling product | TRPA1, TRPV2, TRPV1 | CYP1A2 481/4885ALDH1A1 37/4885TDP1 909/4885 |
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | CYP1A2 385/4885ALDH1A1 40/4885TDP1 880/4885 |
| US-20120010114-A1 | ACETALS AS PERFUMING INGREDIENTS | CBR1, CBR3, C9 | CYP1A2 84/4885ALDH1A1 131/4885TDP1 2948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.