SCHEMBL7002805

SCHEMBL7002805

O=C(O)Cc1c(-c2ccc(Cl)cc2)c(-c2ccccc2)c2n1CCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGES O14684 3/20 0.78
ALOX5 P09917 8/20 0.63
PTGS1 P23219 4/20 0.63
PTGS2 P35354 2/20 0.63
ALOX5AP P20292 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6475572 1.00 PTGES (0.78) PTGESALOX5PTGS1PTGS2ALOX5AP
SCHEMBL9458734 0.92 PTGES (0.65) PTGESALOX5PTGS1PTGS2ALOX5AP
SCHEMBL6487112 0.88 PTGES (0.61) PTGESALOX5PTGS1PTGS2ALOX5AP
SCHEMBL6476339 0.81 PTGES (0.65) PTGESALOX5PTGS1PTGS2ALOX5AP
Licofelone SCHEMBL237833 0.77 ALOX5 (1.00) PTGESALOX5PTGS1PTGS2ALOX5AP
SCHEMBL8594214 0.77 PTGES (0.74) PTGESALOX5PTGS1
SCHEMBL6476356 0.76 PTGES (0.58) PTGESALOX5PTGS1PTGS2ALOX5AP
SCHEMBL6485915 0.76 PTGES (0.58) PTGESALOX5PTGS1PTGS2ALOX5AP
SCHEMBL6486937 0.76 PTGES (0.58) PTGESALOX5PTGS1
SCHEMBL6484148 0.76 PTGES (0.58) PTGESALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245275-A1 SURFACTANT PREPARATIONS FOR PULMONARY DELIVERY, AND METHODS FOR THE PREPARATION AND USE THEREOF MOLECULAR EXPRESS, INC. (US) 2025-11-27 WO disclosed
CN-115028695-B Th1 and CTL epitope peptide pool based on LTBI-RD related protein and application thereof 中国人民解放军总医院第八医学中心 2024-05-17 CN disclosed
EP-4226158-A1 METHODS OF DIAGNOSING TUBERCULOSIS AND DIFFERENTIATING BETWEEN ACTIVE AND LATENT TUBERCULOSIS Cepheid (US) 2023-08-16 EP disclosed
CN-114736276-B CTL epitope peptide of mycobacterium tuberculosis LTBI-RD related protein antigen and application thereof 中国人民解放军总医院第八医学中心 2023-08-01 CN disclosed
CN-116348767-A Method for diagnosing tuberculosis and distinguishing active tuberculosis from latent tuberculosis 西菲伊德公司 2023-06-27 CN disclosed
WO-2022076428-A1 METHODS OF DIAGNOSING TUBERCULOSIS AND DIFFERENTIATING BETWEEN ACTIVE AND LATENT TUBERCULOSIS CEPHEID (US) 2022-04-14 WO disclosed
US-20220106627-A1 METHODS OF DIAGNOSING TUBERCULOSIS AND DIFFERENTIATING BETWEEN ACTIVE AND LATENT TUBERCULOSIS CEPHEID (US) 2022-04-07 US disclosed
EP-1246825-B1 FUSED PYRROLE COMPOUNDS, PHARMACEUTICAL AGENTS CONTAINING THE SAME, AND THE USE THEREOF MERCKLE GMBH (DE) 2003-12-17 EP disclosed