Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | XDH | P47989 | 1/20 | 0.63 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.63 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL1065186 | 1.00 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL1023306 | 1.00 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL18189917 | 1.00 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL2167068 | 1.00 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Guanine SCHEMBL37966 | 0.89 | PNP (0.59) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL4579097 | 0.85 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Hypoxanthine SCHEMBL16096397 | 0.85 | ALDH1A1 (0.58) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| 2,6-Diaminopurine SCHEMBL23292805 | 0.84 | PNP (0.53) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Guanine SCHEMBL2636587 | 0.83 | PNP (0.51) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL6227732 | 0.81 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB Pharma Inc. (CA) | 2019-07-24 | — | — | EP | claimed |
| WO-2018049534-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | claimed |
| US-20030129616-A1 | Use of a mutation in the gene for the beta3-subunit of human g-protein | SNIP BIOTECH GMBH & CO. KG (DE) | 2003-07-10 | — | — | US | claimed |
| US-20030129616-A1 | Use of a mutation in the gene for the beta3-subunit of human g-protein | SNIP BIOTECH GMBH & CO. KG (DE) | 2003-07-10 | — | — | US | disclosed |
| EP-1268852-A1 | USE OF A MUTATION IN THE GENE FOR THE BETA-3-SUBUNIT OF HUMAN G-PROTEIN | Siffert, Winfried (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001057246-A1 | USE OF A MUTATION IN THE GENE FOR THE β3-SUBUNIT OF HUMAN G-PROTEIN | SIFFERT WINFRIED (DE) | 2001-08-09 | — | — | WO | disclosed |