Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 3/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Diaminopurine SCHEMBL23292805 | 0.95 | PNP (0.53) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL2636587 | 0.93 | PNP (0.51) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL2528337 | 0.91 | PNP (0.72) | PNPGDAKDM4EMEN1ALDH1A1 | |
| Guanine SCHEMBL79001 | 0.91 | PNP (0.72) | PNPGDAKDM4EMEN1ALDH1A1 | |
| Guanine SCHEMBL2529420 | 0.91 | PNP (0.72) | PNPGDAKDM4EMEN1ALDH1A1 | |
| Guanine SCHEMBL5097009 | 0.89 | PNP (0.47) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL18189917 | 0.89 | PI4KA (0.63) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL2167068 | 0.89 | PI4KA (0.63) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL1023306 | 0.89 | PI4KA (0.63) | PNPPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL7002960 | 0.89 | PI4KA (0.63) | PNPPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240052345-A1 | PHARMACEUTICAL COMPOSITION | RIKEN (JP) | 2024-02-15 | — | — | US | claimed |
| EP-4268830-A1 | PHARMACEUTICAL COMPOSITION | RIKEN (JP) | 2023-11-01 | — | — | EP | claimed |
| US-20230235325-A1 | Compositions and Methods for Treating Huntington's Disease and Related Disorders | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2023-07-27 | — | — | US | claimed |
| US-11338010-B2 | Systems, methods, and kits for diagnostics and treatment of viral respiratory infection | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2022-05-24 | — | — | US | claimed |
| US-20210355480-A1 | Method For Creating Reference Cell Lines With Simultaneous Genetic Variants And Accurate Quantification Of Alelle Frequency | LU YABIN (US) | 2021-11-18 | — | — | US | claimed |
| US-20210299209-A1 | SYSTEMS, METHODS, AND KITS FOR DIAGNOSTICS AND TREATMENT OF VIRAL RESPIRATORY INFECTION | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2021-09-30 | — | — | US | claimed |
| US-20210299207-A1 | SYSTEMS, METHODS, AND KITS FOR DIAGNOSTICS AND TREATMENT OF VIRAL RESPIRATORY INFECTION | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2021-09-30 | — | — | US | claimed |
| EP-3760204-A1 | MEDICAMENT FOR PREVENTION OR TREATMENT OF HUNTINGTON'S DISEASE | Medizinische Universität Graz (AT) | 2021-01-06 | — | — | EP | claimed |
| US-20190055552-A1 | Compositions and Methods for Treating Huntington's Disease and Related Disorders | THE CHILDREN'S HOSPITAL OF PHILADELPHIA | 2019-02-21 | — | — | US | claimed |
| WO-2017062983-A1 | COMPOSITIONS AND METHODS FOR TREATING HUNTINGTON'S DISEASE AND RELATED DISORDERS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2017-04-13 | — | — | WO | claimed |
| US-12042516-B2 | Therapy for polyglutamine (polyQ) diseases | STEMINENT BIOTHERAPEUTICS INC. (TW) | 2024-07-23 | — | — | US | disclosed |
| US-20240226203-A9 | COMPOSITIONS AND METHODS OF TREATING HUNTINGTON'S DISEASE | VOYAGER THERAPEUTICS, INC. | 2024-07-11 | — | — | US | disclosed |
| WO-2024142058-A1 | PRIDOPIDINE FOR TREATING JUVENILE HUNTINGTON'S DISEASE | PRILENIA NEUROTHERAPEUTICS LTD. (IL) | 2024-07-04 | — | — | WO | disclosed |
| US-12016858-B2 | Methods for the treatment of abnormal involuntary movement disorders | AUSPEX PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| WO-2024121347-A1 | ANTI-HUNTINGTIN ANTIBODIES | ALCHEMAB THERAPEUTICS LTD (GB) | 2024-06-13 | — | — | WO | disclosed |
| US-20030181694-A1 | Light-emitting material and organic light-emitting device | SAMSUNG ELECTRONICS CO., LTD (KR) | 2003-09-25 | — | — | US | disclosed |
| WO-2003023016-A2 | METHOD FOR PRODUCING FINE CHEMICALS | DEGUSSA AG (DE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003001615-A1 | LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE | SHOWA DENKO K. K. (JP) | 2003-01-03 | — | — | WO | disclosed |
| EP-1224199-A1 | TRANSGENIC MICE CONTAINING TRP GENE DISRUPTIONS | Deltagen, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030798-A1 | TRANSGENIC MICE CONTAINING TRP GENE DISRUPTIONS | DELTAGEN, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181694-A1 | Light-emitting material and organic light-emitting device | MAP1LC3C, LAGE3, MAP1LC3A | PNP 2034/4885PI4KA 3996/4885PI4K2B 4171/4885 |
| US-20240052345-A1 | PHARMACEUTICAL COMPOSITION | RNASEH1, RNASE1, DIS3 | PNP 212/4885PI4KA 3891/4885PI4K2B 3870/4885 |
| US-12016858-B2 | Methods for the treatment of abnormal involuntary movement disorders | CKMT1A; CKMT1B, GYS1, MUSK | PNP 1535/4885PI4KA 4467/4885PI4K2B 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.