SCHEMBL7003190

SCHEMBL7003190

O=C(Cc1ccccc1)C(=O)C(=O)Cc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.80
CES2 O00748 2/20 0.80
FNTA P49354 2/20 0.64
FNTB P49356 2/20 0.64
AKR1B1 P15121 1/20 0.64
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
CTBP2 P56545 1/20 0.50
EPHX2 P34913 1/20 0.50
PAM P19021 2/20 0.48
TSHR P16473 2/20 0.48
ABCC4 O15439 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
PTGS1 P23219 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27619700 0.90 CES1 (0.73) CES1CES2FNTAFNTBAKR1B1
SCHEMBL574185 0.89 CES1 (1.00) CES1CES2FNTAFNTBAKR1B1
SCHEMBL27842681 0.89 CES1 (0.64) CES1CES2FNTAFNTBAKR1B1
SCHEMBL27842713 0.87 CES1 (0.61) CES1CES2FNTAFNTBAKR1B1
SCHEMBL28790015 0.87 CES1 (0.61) CES1CES2FNTAFNTBAKR1B1
SCHEMBL27823588 0.87 CES1 (0.61) CES1CES2FNTAFNTBAKR1B1
Hydrochloric Acid SCHEMBL3111570 0.86 CES1 (0.94) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28203540 0.84 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL43235 0.84 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL3408866 0.82 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0239391-B1 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof KUMIAI CHEMICAL INDUSTRY CO (JP) 1994-03-02 EP claimed
EP-0239391-A2 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-30 EP claimed
JP-62195307-A None JP disclosed
JP-1146869-A None JP disclosed
JP-2085213-A None JP disclosed
JP-1163171-A None JP disclosed
JP-63239267-A None JP disclosed
CN-117691175-A Polymer solid electrolyte and metal lithium battery 华南师范大学 2024-03-12 CN disclosed
CN-101591281-A Phosphonate compounds having immunomodulatory activity GILEAD SCIENCES INC (US) 2009-12-02 CN disclosed
CN-101410120-A Anti-inflammatory phosphonate compounds GILEAD SCIENCES INC (US) 2009-04-15 CN disclosed
CN-1780630-A Phosphonate compounds having immunomodulatory activity GILEAD SCIENCES INC (US) 2006-05-31 CN disclosed
EP-0239391-B1 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof KUMIAI CHEMICAL INDUSTRY CO (JP) 1994-03-02 EP disclosed
JP-H0285213-A ANTIBACTERIAL AND ANTIFUNGAL AGENT IHARA CHEM IND CO LTD 1990-03-26 JP disclosed
US-4871751-A 1,2,6-Triphenyl-4(1H)-pyridinone derivatives, and their use as fungicides KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-10-03 US disclosed
JP-H01163171-A 4(1H)-PYRIDINONE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL GERMICIDE KUMIAI CHEM IND CO LTD 1989-06-27 JP disclosed
JP-H01146869-A 4(1H)-PYRIDINONE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE KUMIAI CHEM IND CO LTD 1989-06-08 JP disclosed
JP-S63239267-A 4(1H)-PYRIDINONE DERIVATIVE AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL PURPOSES KUMIAI CHEM IND CO LTD 1988-10-05 JP disclosed
US-4757081-A Agriculture, horticulture KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-07-12 US disclosed
EP-0239391-A2 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-30 EP disclosed
JP-S62195307-A FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE KUMIAI CHEM IND CO LTD 1987-08-28 JP disclosed