Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22432734 | 0.83 | TSHR (0.36) | TDP1TSHRKMT2ANR1H2NR1H3 | |
| SCHEMBL9836829 | 0.81 | NPC1 (0.49) | LCKTDP1L3MBTL1MEN1TSHR | |
| SCHEMBL7003112 | 0.80 | ALDH1A1 (0.35) | L3MBTL1LMNAMEN1TSHRKMT2A | |
| SCHEMBL7004266 | 0.80 | TERT (0.46) | MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5310824 | 0.76 | TDP1 (0.34) | LCKTDP1L3MBTL1TSHRFAAH | |
| SCHEMBL28486147 | 0.75 | FFAR1 (0.32) | TDP1L3MBTL1LMNAMEN1TSHR | |
| SCHEMBL29644739 | 0.74 | LCK (0.57) | LCKTDP1L3MBTL1LMNAMEN1 | |
| SCHEMBL22418729 | 0.74 | FFAR1 (0.34) | TDP1L3MBTL1LMNAMEN1TSHR | |
| SCHEMBL21867404 | 0.73 | NR1H2 (0.35) | LCKTDP1L3MBTL1CES1NR1H2 | |
| SCHEMBL14757433 | 0.73 | CDC25A (0.43) | CES1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185531-B1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | WELLA AG (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6570019-B2 | Hair dyes; uniformity, stability | WELLA AG (DE) | 2003-05-27 | — | — | US | disclosed |
| US-20030055268-A1 | Cationic pyrrolo-pyrrol-derivatives, method for producing them and colorants for keratin fibres, containing these compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-03-20 | — | — | US | disclosed |
| EP-1185531-A1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001062759-A1 | CATIONIC PYRROLO-PYRROL-DERIVATIVES, METHOD FOR PRODUCING THEM AND COLORANTS FOR KERATIN FIBRES, CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055268-A1 | Cationic pyrrolo-pyrrol-derivatives, method for producing them and colorants for keratin fibres, containing these compounds | KRT18, IK, PYCR1 | LCK 918/4885TDP1 1267/4885L3MBTL1 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.