Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.58 |
| ▸ | CA2 | P00918 | 11/20 | 0.58 |
| ▸ | CA12 | O43570 | 8/20 | 0.58 |
| ▸ | CA9 | Q16790 | 8/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994970 | 0.84 | CA2 (0.46) | CA1CA2CA12CA9CA7 | |
| SCHEMBL7002958 | 0.83 | CA2 (0.40) | CA1CA2CA12CA9IDO1 | |
| SCHEMBL7003386 | 0.83 | CA2 (0.49) | CA1CA2CA12CA9CA7 | |
| SCHEMBL6999688 | 0.82 | PTGS2 (0.60) | CA1CA2CA12CA9PTPN7 | |
| SCHEMBL7002002 | 0.81 | PTGS2 (0.56) | CA1CA2CA12CA9CA4 | |
| SCHEMBL7000106 | 0.80 | CA2 (0.53) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6998878 | 0.80 | PTGS2 (0.57) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6992672 | 0.80 | PTGS2 (0.51) | — | |
| SCHEMBL6999710 | 0.79 | CA2 (0.49) | CA1CA2CA12CA9 | |
| SCHEMBL6994360 | 0.79 | CHRNA7 (0.44) | CA1CA2CA9ALDH1A1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |