Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869663 | 0.77 | MAPT (0.36) | KMT2AP2RX7 | |
| Hydrochloric Acid SCHEMBL7333482 | 0.69 | MMP3 (0.38) | P2RX7 | |
| SCHEMBL11584605 | 0.66 | KMT2A (0.56) | KMT2A | |
| SCHEMBL2195728 | 0.64 | MEN1 (0.41) | TRPM8KMT2A | |
| SCHEMBL1417680 | 0.64 | PDK1 (0.34) | — | |
| SCHEMBL31132517 | 0.62 | MMP3 (0.41) | — | |
| SCHEMBL9337496 | 0.62 | FGFR1 (0.47) | KMT2ATDP1 | |
| SCHEMBL24869246 | 0.62 | P2RX7 (0.31) | P2RX7 | |
| Hydrochloric Acid SCHEMBL7324922 | 0.61 | MMP3 (0.40) | — | |
| SCHEMBL22207807 | 0.60 | ALDH1A1 (0.46) | KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |