Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29443981 | 1.00 | KMT2A (0.56) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL16398977 | 0.91 | L3MBTL1 (0.60) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL23631448 | 0.89 | MEN1 (0.56) | KMT2AMEN1L3MBTL1ACHEPIM1 | |
| 3-Formylindole SCHEMBL16402731 | 0.88 | IMPDH2 (0.51) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL19760135 | 0.87 | MEN1 (0.55) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL3899414 | 0.85 | MEN1 (0.53) | KMT2AMEN1L3MBTL1ACHEALDH1A1 | |
| SCHEMBL31022652 | 0.84 | MEN1 (0.53) | KMT2AMEN1L3MBTL1ACHEPIM1 | |
| SCHEMBL2942891 | 0.84 | MEN1 (0.53) | KMT2AMEN1L3MBTL1ACHEPIM1 | |
| SCHEMBL2942893 | 0.84 | MEN1 (0.53) | KMT2AMEN1L3MBTL1ACHEPIM1 | |
| SCHEMBL15902182 | 0.83 | HTR6 (0.46) | KMT2AMEN1L3MBTL1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480537-B | Quinazolinone [2,3-a ] carboline derivative and preparation method and application thereof | 广西师范大学 | 2022-05-10 | — | — | CN | claimed |
| CN-110143911-B | Preparation method of N- (indole-N-formyl) -alpha-amino amide derivative | 浙江大学 | 2021-12-17 | — | — | CN | claimed |
| CN-113480537-A | Quinazolinone [2,3-a ] carboline derivative and preparation method and application thereof | 广西师范大学 | 2021-10-08 | — | — | CN | claimed |
| CN-116535386-B | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2025-05-27 | — | — | CN | disclosed |
| EP-3426658-B1 | MALASSEZIN AND ANALOGS THEREOF AS SKIN BRIGHTENING AGENTS | VERSICOLOR TECH LLC (US) | 2025-01-15 | — | — | EP | disclosed |
| US-12012411-B2 | Viral replication inhibitors | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-18 | — | — | US | disclosed |
| WO-2024010732-A1 | SMALL MOLECULE INHIBITORS OF GLUTAMINE TRANSPORTER ASCT2 AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-01-11 | — | — | WO | disclosed |
| CN-116535386-A | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2023-08-04 | — | — | CN | disclosed |
| US-20230131535-A1 | ARYLMETHYLENE AROMATIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D. E. SHAW RESEARCH, LLC | 2023-04-27 | — | — | US | disclosed |
| US-11420944-B2 | Voltage-dependent t-type calcium channel blocker | NIPPON CHEMIPHAR CO., LTD. (JP) | 2022-08-23 | — | — | US | disclosed |
| CN-114727992-A | Arylmethylene aromatic compounds as Kv1.3 potassium Shaker channel blockers | D·E·萧尔研究有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| US-6207679-B1 | FOR INHIBITING GROWTH OF BACTERIAL MICROORGANISMS | SEPRACOR, INC. | 2001-03-27 | — | — | US | disclosed |
| WO-2001016318-A2 | SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME | GENENTECH, INC. (US) | 2001-03-08 | — | — | WO | disclosed |
| US-6172084-B1 | BACTERICIDES AGAINST ANTIBIOTIC RESISTANT STRAINS OF STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS | SEPRACOR, INC. | 2001-01-09 | — | — | US | disclosed |
| US-6103905-A | EFFECTIVE AGAINST DRUG RESISTANT GRAMPOSITIVE BACTERIAL INFECTIONS; ANTIBIOTICS | SEPRACOR, INC. (US) | 2000-08-15 | — | — | US | disclosed |
| WO-2000034265-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS | SEPRACOR, INC. (US) | 2000-06-15 | — | — | WO | disclosed |
| EP-0991623-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS, USES AND COMPOSITIONS RELATED THERETO | SEPRACOR, INC. (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057931-A2 | QUINOLINE-INDOLE ANTIMICROBIAL AGENTS, USES AND COMPOSITIONS RELATED THERETO | SEPRACOR INC. (US) | 1998-12-23 | — | — | WO | disclosed |
| US-5554753-A | Catalytic enantioselective synthesis of α-amino acid derivatives by phase-transfer catalysis | INDIANA UNIVERSITY FOUNDATION (US) | 1996-09-10 | — | — | US | disclosed |
| WO-1995006029-A1 | ENANTIOSELECTIVE SYNTHESIS OF ALPHA - ALKYLATED AMINO ACID DERIVATIVES BY PHASE - TRANSFER CATALYSIS | INDIANA UNIVERSITY FOUNDATION (US) | 1995-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11420944-B2 | Voltage-dependent t-type calcium channel blocker | CACNA1I, CACNA1G, CACNA1E | KMT2A 1735/4885MEN1 2133/4885L3MBTL1 1700/4885 |
| US-20230131535-A1 | ARYLMETHYLENE AROMATIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | KCNJ2, KCNA3, KCNK3 | KMT2A 245/4885MEN1 1980/4885L3MBTL1 3877/4885 |
| US-12012411-B2 | Viral replication inhibitors | EIF2AK2, MAVS, ZC3HAV1 | KMT2A 2425/4885MEN1 3390/4885L3MBTL1 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.