Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 6/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005281 | 0.84 | TLR8 (0.49) | TLR8SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7005330 | 0.81 | TLR8 (0.51) | TLR8GPBAR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7003762 | 0.79 | TLR8 (0.49) | TLR8GPBAR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7004330 | 0.77 | ALDH1A1 (0.54) | TLR8SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7007753 | 0.75 | SCN9A (0.40) | TLR8DHODHNPC1RAB9AKDM4E | |
| SCHEMBL16836333 | 0.69 | TLR8 (1.00) | TLR8DHODHSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16310381 | 0.68 | AR (0.59) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2608869 | 0.68 | TLR8 (0.54) | TLR8GPBAR1SMN1; SMN2MEN1POLB | |
| SCHEMBL741255 | 0.68 | KDM4E (0.61) | TLR8GPBAR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7005082 | 0.66 | AR (0.39) | TLR8SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |