Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005281 | 0.87 | TLR8 (0.49) | TLR8NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7004498 | 0.81 | TLR8 (0.52) | TLR8GPBAR1CYSLTR1NPC1RAB9A | |
| SCHEMBL22033267 | 0.80 | TLR8 (0.56) | TLR8GPBAR1CYSLTR1NPC1RAB9A | |
| SCHEMBL7004330 | 0.78 | ALDH1A1 (0.54) | TLR8NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7003762 | 0.74 | TLR8 (0.49) | TLR8GPBAR1CYSLTR1NPC1RAB9A | |
| SCHEMBL7004327 | 0.74 | S1PR1 (0.39) | TLR8NPC1RAB9AMEN1MAPT | |
| SCHEMBL7004490 | 0.74 | GPBAR1 (0.64) | TLR8GPBAR1CYSLTR1CYSLTR2NPC1 | |
| SCHEMBL741255 | 0.71 | KDM4E (0.61) | TLR8GPBAR1CYSLTR1CYSLTR2NPC1 | |
| SCHEMBL16575398 | 0.71 | MAPT (0.41) | TLR8MEN1POLBMAPTKMT2A | |
| SCHEMBL30060467 | 0.70 | MEN1 (0.61) | TLR8GPBAR1CYSLTR1CYSLTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |